Study of the regenerative effects of xenogeneic transplantation in knee articular cartilage defects
نویسندگان
چکیده
INTRODUCTION: While allogeneic transplantation has attracted much attention in regenerative medicine, animal models approximating safety and efficacy are continued to be explored in translational research because cell sources and transplantation modalities are diverse. Currently, we are preparing for a clinical study using allogeneic chondrocyte sheets for articular cartilage regeneration. In the present study, we investigated the regenerative effects of human chondrocyte sheets for articular cartilage regeneration in a xenogeneic transplantation model using immune deficient rats.
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